Use between late afternoon and bedtime.
Melatonin plays an important role in the induction of sleep.
Several double-blind trials have shown melatonin supplementation to be very effective in promoting sleep.
Low melatonin secretion at night are thought to be an extremely common cause of insomnia in the elderly, while in younger individuals this is less of a factor.
Melatonin may help shift workers adjust to new sleep patterns when shifts are changing.
Use during and for 5 days after travel that crosses time lines.
Several double-blind studies have shown 3 to 5 mg of melatonin to be very effective in relieving jet lag.
Seasonal Affect Disorder:
Melatonin supplementation may improve SAD because it not only increases brain melatonin levels, but also because it may suppress cortisol secretion.
Adults: dissolve 1-3 tablets under the tongue once daily, at bedtime only or as directed by a health care practitioner. For use beyond 4 weeks, consult a health care practitioner. Keep out of the reach of children.
Children: not suitable for use in children unless specifically recommended and monitored by a health care practitioner.
Pregnancy and Nursing: as the effects of melatonin during pregnancy and lactation have not been sufficiently evaluated, it should not be used during these times.
Melatonin (non-animal source) ................................ 3 mg
Melatonin may enhance the anticancer effects of certain chemotherapy agents.
Melatonin has been used to be helpful in treating withdrawal reactions from people addicted to benzodiazepine drugs (Valium® and Halcyon®).
Melatonin levels are typically lowered by beta-blocker drugs like Inderal® and Atenolol® as well as by other drugs used in treating high blood pressure or angina (verapamil, aspirin, and other non-steroidal anti-inflammatory drugs).
Melatonin levels may be increased by fluoxetine (Prozac).
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